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Fundamentals of Protein NMR Spectroscopy Focus on Structural Bio Springer

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所在地：Princeton, North Carolina, 美國
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Book title
Fundamentals of Protein NMR Spectroscopy Focus on Structural Bio
ISBN
9781402034992
Subject Area
Science, Medical
Publication Name
Fundamentals of Protein NMR Spectroscopy
Item Length
9.3 in
Publisher
Springer Netherlands
Subject
Spectroscopy & Spectrum Analysis, Life Sciences / Biophysics, Research
Publication Year
2005
Series
Focus on Structural Biology Ser.
Type
Textbook
Format
Hardcover
Language
English
Item Height
0.6 in
Author
T. Kevin Hitchens, Gordon S. Rule
Item Width
6.1 in
Item Weight
74.4 Oz
Number of Pages
Xxvi, 532 Pages

關於產品

Product Information

NMR spectroscopy has proven to be a powerful technique to study the structure and dynamics of biological macromolecules. Fundamentals of Protein NMR Spectroscopy is a comprehensive textbook that guides the reader from a basic understanding of the phenomenological properties of magnetic resonance to the application and interpretation of modern multi-dimensional NMR experiments on 15N/13C-labeled proteins. Beginning with elementary quantum mechanics, a set of practical rules is presented and used to describe many commonly employed multi-dimensional, multi-nuclear NMR pulse sequences. A modular analysis of NMR pulse sequence building blocks also provides a basis for understanding and developing novel pulse programs. This text not only covers topics from chemical shift assignment to protein structure refinement, as well as the analysis of protein dynamics and chemical kinetics, but also provides a practical guide to many aspects of modern spectrometer hardware, sample preparation, experimental set-up, and data processing. End of chapter exercises are included to emphasize important concepts. Fundamentals of Protein NMR Spectroscopy not only offer students a systematic, in-depth, understanding of modern NMR spectroscopy and its application to biomolecular systems, but will also be a useful reference for the experienced investigator.

Product Identifiers

Publisher
Springer Netherlands
ISBN-10
1402034997
ISBN-13
9781402034992
eBay Product ID (ePID)
48237561

Product Key Features

Author
T. Kevin Hitchens, Gordon S. Rule
Publication Name
Fundamentals of Protein NMR Spectroscopy
Format
Hardcover
Language
English
Subject
Spectroscopy & Spectrum Analysis, Life Sciences / Biophysics, Research
Publication Year
2005
Series
Focus on Structural Biology Ser.
Type
Textbook
Subject Area
Science, Medical
Number of Pages
Xxvi, 532 Pages

Dimensions

Item Length
9.3 in
Item Height
0.6 in
Item Width
6.1 in
Item Weight
74.4 Oz

Additional Product Features

Intended Audience
Scholarly & Professional
Series Volume Number
5
Number of Volumes
1 Vol.
Lc Classification Number
Qh505
Reviews
From the reviews: "I think this may become a very useful addition to the repertoire of books on biomolecular NMR spectroscopy. This text is more complete than the well-known book by Cavanagh et al., in the derivation of theoretical results and at the same time it contains more practical information. It is more up to date compared with the 1996 edition of Cavanagh (for instance by including residual dipolar couplings) and the inclusion of exercises is also an attractive feature." (Prof. Dr. Rob Kaptein, Bijvoet Center for Biomolecular Research, The Netherlands)
Table of Content
NMR Spectroscopy.- Practical Aspects of Acquiring NMR Spectra.- to Signal Processing.- Quantum Mechanical Description of NMR.- Quantum Mechanical Description of a One Pulse Experiment.- The Density Matrix & Product Operators.- Scalar Coupling.- Coupled Spins: Density Matrix and Product Operator Formalism.- Two Dimensional Homonuclear J-Correlated Spectroscopy.- Two Dimensional Heteronuclear J-Correlated Spectroscopy.- Coherence Editing: Pulsed-Field Gradients and Phase Cycling.- Quadrature Detection in Multi-Dimensional NMR Spectroscopy.- Resonance Assignments: Homonuclear Methods.- Resonance Assignments: Heteronuclear Methods.- Practical Aspects of N-Dimensional Data Acquisition and Processing.- Dipolar Coupling.- Protein Structure Determination.- Exchange Processes.- Nuclear Spin Relaxation and Molecular Dynamics.
Copyright Date
2006
Dewey Decimal
620.19204223
Dewey Edition
22
Illustrated
Yes

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