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B Cell Receptor Signaling - 9783319261317
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- Book Title
- B Cell Receptor Signaling
- ISBN
- 9783319261317
- Publication Name
- B Cell Receptor Signaling
- Publisher
- Springer International Publishing A&G
- Subject
- Medicine, Biology
- Series
- Current Topics in Microbiology and Immunology
- Publication Year
- 2016
- Type
- Textbook
- Format
- Hardcover
- Language
- English
- Item Height
- 235 mm
- Item Width
- 155 mm
- Item Weight
- 4912 g
- Number of Pages
- 231 Pages
關於產品
Product Information
This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton's Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
Product Identifiers
Publisher
Springer International Publishing A&G
ISBN-13
9783319261317
eBay Product ID (ePID)
223819891
Product Key Features
Series
Current Topics in Microbiology and Immunology
Publication Name
B Cell Receptor Signaling
Format
Hardcover
Language
English
Subject
Medicine, Biology
Publication Year
2016
Type
Textbook
Number of Pages
231 Pages
Dimensions
Item Height
235 mm
Item Width
155 mm
Item Weight
4912 g
Volume
393
Additional Product Features
Country/Region of Manufacture
Switzerland
Editor
Jurgen Wienands, Tomohiro Kurosaki
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商業賣家資料
增值稅識別編號:
- GB 976952259
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