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Mammalian Heme Peroxidases : Diverse Roles in Health and Disease, Hardcover b...

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ISBN
9780367820367
Publication Year
2021
Format
Hardcover
Language
English
Book Title
Mammalian Heme Peroxidases
Author
Clare Hawkins, William M. Nauseef
Publisher
CRC Press LLC
Genre
Science
Topic
Life Sciences / Anatomy & Physiology (See Also Life Sciences / Human Anatomy & Physiology)
Number of Pages
376 Pages

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Product Information

Mammalian heme peroxidase enzymes play a critical role in innate immune responses and disease prevention. The formation of potent chemical oxidants is essential to this protective physiologic activity in immunity. Although highly beneficial in the context of immune defense, it is now well established that peroxidases and their overproduction of oxidants contribute to the initiation and persistence of many chronic inflammatory conditions in the cardiovascular, neurologic, respiratory, renal, and gastrointestinal systems. Peroxidasins, a protein family related to heme peroxidases, play a novel role in tissue biogenesis and matrix assembly, which are also attracting attention in different pathological contexts. Given the diverse roles of mammalian heme peroxidases and the breadth and incidence of pathologies associated with these enzymes, there has been significant interest in modulating peroxidase activity as a therapeutic strategy. This book highlights recent developments in our understanding of the chemistry, biochemistry and biological roles of mammalian peroxidases and their associated oxidants, their involvement in both innate immunity and chronic inflammatory disease in a variety of end organs, and potential therapeutic approaches to modulate and prevent damaging reactions. Key Features Structure and biosynthesis of mammalian peroxidases Reactivity of hypohalous acids with biological substrates Peroxidases in innate immunity Peroxidases in human pathology Modulation of peroxidase-induced biological damage

Product Identifiers

Publisher
CRC Press LLC
ISBN-10
0367820366
ISBN-13
9780367820367
eBay Product ID (ePID)
8050071664

Product Key Features

Book Title
Mammalian Heme Peroxidases
Author
Clare Hawkins, William M. Nauseef
Format
Hardcover
Language
English
Topic
Life Sciences / Anatomy & Physiology (See Also Life Sciences / Human Anatomy & Physiology)
Publication Year
2021
Genre
Science
Number of Pages
376 Pages

Additional Product Features

Lc Classification Number
Qp603.P4m35 2021
Lccn
2021-014716
Dewey Decimal
572.791
Dewey Edition
23
Illustrated
Yes

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