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Book Title
Ultra-High Performance Liquid Chromatography and Its Applications
ISBN
9780470938423
Subject Area
Technology & Engineering, Science
Publication Name
Ultra-High Performance Liquid Chromatography and Its Applications
Item Length
9.5 in
Publisher
Wiley & Sons, Incorporated, John
Subject
Chemistry / Analytic, Chemical & Biochemical
Publication Year
2013
Type
Textbook
Format
Hardcover
Language
English
Item Height
0.9 in
Author
Q. Alan Xu
Item Width
6.4 in
Item Weight
19.2 Oz
Number of Pages
304 Pages

關於產品

Product Information

Explores both the benefits and limitations of new UHPLC technology High performance liquid chromatography (HPLC) has been widely used in analytical chemistry and biochemistry to separate, identify, and quantify compounds for decades. The science of liquid chromatography, however, was revolutionized a few years ago with the advent of ultra-high performance liquid chromatography (UHPLC), which made it possible for researchers to analyze sample compounds with greater speed, resolution, and sensitivity. Ultra-High Performance Liquid Chromatography and Its Applications enables readers to maximize the performance of UHPLC as well as develop UHPLC methods tailored to their particular research needs. Readers familiar with HPLC methods will learn how to transfer these methods to a UHPLC platform and vice versa. In addition, the book explores a variety of UHPLC applications designed to support research in such fields as pharmaceuticals, food safety, clinical medicine, and environmental science. The book begins with discussions of UHPLC method development and method transfer between HPLC and UHPLC platforms. It then examines practical aspects of UHPLC. Next, the book covers: Coupling UHPLC with mass spectrometry Potential of shell particles in fast liquid chromatography Determination of abused drugs in human biological matrices Analyses of isoflavones and flavonoids Therapeutic protein characterization Analysis of illicit drugs The final chapter of the book explores the use of UHPLC in drug metabolism and pharmacokinetics studies for traditional Chinese medicine. With its frank discussions of UHPLC's benefits and limitations, Ultra-High Performance Liquid Chromatography and Its Applications equips analytical scientists with the skills and knowledge needed to take full advantage of this new separation technology.

Product Identifiers

Publisher
Wiley & Sons, Incorporated, John
ISBN-10
0470938420
ISBN-13
9780470938423
eBay Product ID (ePID)
143603065

Product Key Features

Author
Q. Alan Xu
Publication Name
Ultra-High Performance Liquid Chromatography and Its Applications
Format
Hardcover
Language
English
Subject
Chemistry / Analytic, Chemical & Biochemical
Publication Year
2013
Type
Textbook
Subject Area
Technology & Engineering, Science
Number of Pages
304 Pages

Dimensions

Item Length
9.5 in
Item Height
0.9 in
Item Width
6.4 in
Item Weight
19.2 Oz

Additional Product Features

LCCN
2012-035740
Intended Audience
Scholarly & Professional
Lc Classification Number
Qd79.C454u48 2013
Table of Content
Preface vii Contributors ix 1. UHPLC Method Development 1 Shujun Chen and Alireza Kord 2. Method Transfer Between HPLC and UHPLC Platforms 31 Gregory K. Webster, Thomas F. Cullen, and Laila Kott 3. Practical Aspects of Ultrahigh Performance Liquid Chromatography 55 Naijun Wu, Christopher J. Welch, Theresa K. Natishan, Hong Gao, Tilak Chandrasekaran, and Li Zhang 4. Coupling UHPLC with MS: The Needs, Challenges, and Applications 95 Julie Schappler, Serge Rudaz, Jean-Luc Veuthey, and Davy Guillarme 5. The Potential of Shell Particles in Fast Liquid Chromatography 133 Szabolcs Fekete and Jeno Fekete 6. UHPLC Determination of Drugs of Abuse in Human Biological Matrices 169 Fabio Gosetti, Eleonora Mazzucco, and Maria Carla Gennaro 7. UHPLC in the Analyses of Isoflavones and Flavonoids 197 Sylwia Magiera and Irena Baranowska 8. UHPLC for Characterization of Protein Therapeutics 235 Jennifer C. Rea, Yajun Jennifer Wang, and Taylor Zhang 9. UHPLC/MS Analysis of Illicit Drugs 253 Guifeng Jiang, Jason R. Stenzel, Ray Chen, and Diab Elmashni 10. Ultra-High Performance Liquid Chromatography - Mass Spectrometry and Its Application 271 Zhili Xiong, Ying Deng, and Famei Li Index 291
Copyright Date
2013
Dewey Decimal
543/.84
Dewey Edition
23
Illustrated
Yes

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