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Quasispecies Equation and Classical Population Models, Paperback by Cerf, Rap...

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Book Title
Quasispecies Equation and Classical Population Models
ISBN
9783031086656
Publication Year
2023
Series
Probability Theory and Stochastic Modelling Ser.
Type
Textbook
Format
Trade Paperback
Language
English
Publication Name
Quasispecies Equation and Classical Population Models
Author
Joseba Dalmau, Raphaël Cerf
Item Length
9.3in
Publisher
Springer International Publishing A&G
Item Width
6.1in
Item Weight
13.8 Oz
Number of Pages
X, 242 Pages

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Product Information

This monograph studies a series of mathematical models of the evolution of a population under mutation and selection. Its starting point is the quasispecies equation, a general non-linear equation which describes the mutation-selection equilibrium in Manfred Eigen's famous quasispecies model. A detailed analysis of this equation is given under the assumptions of finite genotype space, sharp peak landscape, and class-dependent fitness landscapes. Different probabilistic representation formulae are derived for its solution, involving classical combinatorial quantities like Stirling and Euler numbers. It is shown how quasispecies and error threshold phenomena emerge in finite population models, and full mathematical proofs are provided in the case of the Wright-Fisher model. Along the way, exact formulas are obtained for the quasispecies distribution in the long chain regime, on the sharp peak landscape and on class-dependent fitness landscapes. Finally, several other classical population models are analyzed, with a focus on their dynamical behavior and their links to the quasispecies equation. This book will be of interest to mathematicians and theoretical ecologists/biologists working with finite population models.

Product Identifiers

Publisher
Springer International Publishing A&G
ISBN-10
3031086651
ISBN-13
9783031086656
eBay Product ID (ePID)
15062159678

Product Key Features

Author
Joseba Dalmau, Raphaël Cerf
Publication Name
Quasispecies Equation and Classical Population Models
Format
Trade Paperback
Language
English
Publication Year
2023
Series
Probability Theory and Stochastic Modelling Ser.
Type
Textbook
Number of Pages
X, 242 Pages

Dimensions

Item Length
9.3in
Item Width
6.1in
Item Weight
13.8 Oz

Additional Product Features

Series Volume Number
102
Number of Volumes
1 Vol.
Lc Classification Number
Qa1-939
Reviews
"The text is written in an easy-to-read style and is suitable for use in various courses, including probability theory, Markov chains, mathematical ecology and population dynamics. The book can be expected to provide several ideas for further investigation of finite population models." (Attila Dénes, zbMATH 1507.92072, 2023), "This book is a welcome and timely addition to the existing literature on rigorous mathematical analysis of various genetics models, with a special focus on a careful understanding of the impact of stochastic effects. The book is written with the potential reader in mind, such that it is a real pleasure to read. It should be interesting to anyone working at the interface of mathematics and population genetics." (Artem S. Novozhilov, Mathematical Reviews, August, 2023) "The text is written in an easy-to-read style and is suitable for use in various courses, including probability theory, Markov chains, mathematical ecology and population dynamics. The book can be expected to provide several ideas for further investigation of finite population models." (Attila Dénes, zbMATH 1507.92072, 2023)
Table of Content
1. Introduction.- Part I.Finite Genotype Space.- 2. The Quasispecies equation.- 3. Non-Overlapping Generations.- 4. Overlapping Generations.- 5. Probabilistic Representations.- Part II. The Sharp Peak Landscape.- 6. Long Chain Regime.- 7. Error Threshold and Quasispecies.- 8. Probabilistic Derivation.- 9. Summation of the Series.- 10. Error Threshold in Infinite Populations.- Part III. Error Threshold in Finite Populations.- 11.Phase Transition.- 12. Computer Simulations.- 13. Heuristics.- 14. Shape of the Critical Curve.- 15. Framework for the Proofs.- Part IV. Proof for Wright-Fisher.- 16. Strategy of the Proof.- 17. The Non-Neutral Phase M.- 18. Mutation Dynamics.- 19. The Neutral Phase N.- 20. Synthesis.- Part V. Class-Dependent Fitness Landscapes.- 21. Generalized Quasispecies Distributions.- 22. Error Threshold.- 23. Probabilistic Representation.- 24. Probabilistic Interpretations.- 25. Infinite Population Models.- Part VI. A Glimpse at the Dynamics.- 26. Deterministic Level.- 27. From Finite to Infinite Population.- 28. Class-Dependent Landscapes.- A. Markov Chains and Classical Results.- References.- Index.
Copyright Date
2022
Topic
Probability & Statistics / General, Life Sciences / General, General, Life Sciences / Biology
Dewey Decimal
570.15195
Dewey Edition
23
Illustrated
Yes
Genre
Science, Mathematics

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