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Hyaluronan : Biological and Medical Implications, Hardcover by Pomin, Vitor H...

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ISBN
9781631178085
Format
Hardcover
Language
English
Book Title
Hyaluronan : Biological and Medical Implications
Illustrator
Yes
Author
Vitor H. Pomin
Item Length
9.1 in
Publisher
NOVA Science Publishers, Incorporated
Genre
Science
Topic
Life Sciences / Biochemistry, Life Sciences / Anatomy & Physiology (See Also Life Sciences / Human Anatomy & Physiology), Chemistry / General
Item Width
6.1 in
Item Weight
13.5 Oz
Number of Pages
123 Pages

關於產品

Product Information

Hyaluronan or hyaluronic acid (HA), the only non-sulfated glycosaminoglycan (GAG) of the body, is structurally composed of disaccharide repeating units of alternating 3-linked N-acetyl -D-glucosamine and 4-linked -D-glucuronic acid. Despite the lack of sulfation and the lowest structural heterogeneity among all GAGs, HA still retains efficient capability in interacting with many molecules, especially functional proteins like growth factors, cytokines, and adhesive proteins involved in angiogenesis, tumour proliferation, migration and invasion. However, the main biological role of HA is to assemble the extracellular matrices of certain soft tissues, such as vitreous humour, synovial fluid, umbilical cord and the intercellular space of the epidermis. HA is the major structure-forming component in the globe of the eye and cornea. For this reason, this GAG can be used to compose ophthalmic solutions. The most famous physicochemical property of HA is its capacity to make gels in solution. This property can be pharmaceutically and industrially useful as either a vehicle to make specific media or biologically active sera. This book, heavily based on recent scientific results from research groups of several countries, will cover many of these aspects of HA, the related enzymes and metabolism in health and disease. The seven chapters are basically centred in: 1) the covalent modifications of HA by serum protein and the biological consequences; 2) the aspects of HA as a function of age; 3) carcinogenesis as a function of HA metabolism; 4) therapeutic applications of HA-related enzymes; 5) characterisation and analyses of HA-based ophthalmic solutions; 6) the role of HA in reproductive medicine; and 7) the role of HA in bone medicine. The contributing authors are renowned scientists in the HA field and this collaborates to the high-quality of this publication.

Product Identifiers

Publisher
NOVA Science Publishers, Incorporated
ISBN-10
1631178083
ISBN-13
9781631178085
eBay Product ID (ePID)
210303525

Product Key Features

Book Title
Hyaluronan : Biological and Medical Implications
Author
Vitor H. Pomin
Format
Hardcover
Language
English
Topic
Life Sciences / Biochemistry, Life Sciences / Anatomy & Physiology (See Also Life Sciences / Human Anatomy & Physiology), Chemistry / General
Illustrator
Yes
Genre
Science
Number of Pages
123 Pages

Dimensions

Item Length
9.1 in
Item Width
6.1 in
Item Weight
13.5 Oz

Additional Product Features

Lc Classification Number
Qp702.H8h92 2014
Table of Content
Covalent Modification of Hyaluronan by Serum Protein & Its Biological Consequence; Aging & Hyaluronan; Biological Synthesis & Catabolism of Hyaluronic Acid During Carcinogenesis; Hyaluronidases: Biological Features & Current Therapeutic Applications; In vitro Characterization & Ophthalmic Applications of Hyaluronan; The Role & Use of Hyaluronan in Reproductive Medicine; Hyaluronan-Coated Bone Graft Substitutes & Their Osteoconductive Properties; Index.
Copyright Date
2014
Lccn
2014-937640
Dewey Decimal
612/.01578
Dewey Edition
23

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